Volume 1 (2015) - Issue 4, April
Improving oral bioavailability of drugs those used as solid dosage forms remains a challenge for the formulation scientists due to solubility problems associated with it. The dissolution rate could be the rate-limiting process in the absorption of a drug from a solid dosage form of relatively insoluble drugs. Solid dispersion techniques have attracted considerable interest of improving the disso...
According to the research by World Health Organisation (WHO), 36 million people die each year due to various health problems. However, this number can be reduced if patients are detected early and treated properly. The expansion and use of electronic nose has many applications in the healthcare and a bio-medical field is rapidly to accelerate over the past 25 years. Many e-nose technologies have g...
Fast-dissolving drug-delivery systems were first developed in the late 1970s as an alternative to tablets, capsules, and syrups for paediatric and geriatric patients who experience difficulties swallowing traditional oral solid- dosage forms. Fast dissolving films have become a novel approach to oral drug delivery system as it provides convenience and ease of use over other dosage forms such as ...
SUSTAIN RELEASE FORMULATION AND EVALUATION OF CIPROFLOXACIN SUSTAIN RELEASE TABLET AND ITS COMPARISON WITH MARKET PRODUCT
In this study an attempt was made to design and evaluate oral sustained release matrix tablets of ciprofloxacin using Methocel K4M CR, HPMC 15 cps, Avicel PH 101 as the retardant polymer. Tablets were prepared by conventional wet granulation technique. Tablets were evaluated for parameters such as weight variation, hardness, friability and drug content. All the formulations showed compliance with ...
Sumatriptan is a potent and selective 5-hydroxytryptamine agonist. It is an effective agent in the treatment of acute migraine attack. Sumatriptan is rapidly but incompletely absorbed following oral administration and undergoes first pass metabolism resulting in a low absolute bioavailability of 15%. The biological half-life of Sumatriptan is about 2.5 hr. The aim was to develop gastro retentive f...
This paper deals with the concept of design and implementation of a low cost model of an arm control moving chair using ATmega8.This moving chair has the ability to move forward, backward, left and right. This basically is done with the movement (tilt) of the accelerometer, and the chair stops when there is no movement of the accelerometer. The values of the three dimensional axis of the accelerom...