Volume 1 (2015) - Issue 7, July
The marine world is largely unexplored that harbors most of the biodiversity. In recent years, marine natural products have yielded a considerable number of drug candidates. Marine microorganisms, whose genetic and biochemical diversity became a rich source of novel chemical entities for the discovery of more effective drugs. Marine microbes specially marine sponges are playing a unique contributi...
A solid dispersion is the dispersion of one or more active ingredients in an inert carrier or matrix at solid state prepared by melting, solvent, or melting-solvent Method. The poor solubility of drug substances in water and their low dissolution rate in the aqueous gastro-intestinal fluids often lead to insufficient bioavailability. If the dissolution rate of the active ingredient in the gastro-i...
Mouth dissolving tablet disintegrate within a minute without drinking water. The purpose of present work was to develop patient friendly tablet for antihypertensive treatment using Benazepril HCL was taste masked by complexing with Indion 204 and formulate as mouth dissolving tablet (MDT). Formulated drug resin complex was characterized by IR, DSC etc. Overall nine mouth dissolving formulations we...