Volume 4 (2018) - Issue 8, August
STUDY OF IN-VITRO α-GLUCOSIDASE INHIBITORY ACTIVITY OF SYZIGIUM AROMATICUM AND ITS HERB DRUG INTERACTION WITH ACARBOSE AND METFORMIN
Background and Aim: Diabetes mellitus is a disorder characterized by the body’s inability to produce insulin, leading to an increased level of blood glucose and manifestation into various complications. Diet can be considered an important factor in prevention or management of diabetes. Spices, apart from their culinary and remedial uses, have been exploited for their pharmacological and physiolo...
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, less side effect, easy use and improved patient compliance. Glimepiride is an anti-diabetic drug with a shorter half life of ~ 5 h, low bioavailability and extensive first pass metabolism due to these limitations required to maintain the therapeutic...