Volume 1 (2015) - Issue 1, January
Clitoria ternatea, commonly known as Butterfly pea, is a medicinal plant belonging to the family Fabaceae. The plant is reported to be used in lithiasis, insect bites, skin diseases, asthma, burning sensation, ascites, inflammation, leucoderma, leprosy, hemicrania, amentia, and pulmonary tuberculosis. It is commonly called “Shankpushpi” in the Sanskrit language where it is reported to be a goo...
The Initial exploratory attempt was made to study the prevalent medicinal flora of Jhansi district of Uttar Pradesh which is a potentially rich heritage of floristic element of medicinal and therapeutical values. The present study deals with angiospermic plants belonging to55 genera and 38 families of Jhansi district for curing various disorders among different ethnic societies. The important gene...
RATIONALE FOR CHANGING INITIAL HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) REGIMEN AMONG HIV/AIDS PATIENTS IN WEST ETHIOPIA
Background: Antiretroviral therapy (ART) is not a cure but it dramatically reduces the rate of morbidity and mortality, and it improves quality of life to people living with HIV/AIDS and it also now considered a manageable chronic disease. Objective: The main objective of this study is to determine the reason for treatment and regimen changes, types of regimen changes, and duration of first initia...
SYNTHESIS OF SOME NOVEL 2-SUBSTITUTED IMINO-7-SUBSTITUTED PHENYL-3, 7-DIHYDRO-2H-[1, 3] THIAZOLO [5, 4-E] – THIAZIN-5-AMINE AS ANTIFUNGAL ACTIVITY
The condensation of 2-imino-5 substituted benzylidene-4-thiazolidinone (1) with thiourea (2) in the presence of glacial acetic acid to gives 2-substituted imino-7-substituted phenyl-3,7-dihydro-2H-[1,3] thiazolo [5,4-e]- thiazin-5-amine (3). The antifungal activities of the compounds (3a-h) were tested against A.niger and A. flavus. The growth of both fungi A. niger and A. flavus are inhibited to ...
In-vitro cytotoxicity testing has become an integral aspect of drug discovery because it is a convenient, cost-effective, and predictive means of characterizing the toxic potential of new chemical entities. The early and routine implementation of this testing is a testament to its prognostic importance for humans. Anticancer activity of different concentrations (20-100) of plant extracts Terminali...
STABILITY INDICATING UV SPECTROSCOPIC METHOD FOR THE ESTIMATION OF METFORMIN HYDROCHLORIDE IN BULK AND TABLETS
Background: Forced degradation studies are used to determine the degradation pathways and degradation products of the active pharmaceutical ingredients that could form during storage and facilitate formulation development, manufacturing and packaging. Aim: To develop and validate simple and precise stability indicating UV Spectrophotometric method for Metformin Hydrochloride in the bulk and tablet...