Volume 1 (2015) - Issue 7, July
The marine world is largely unexplored that harbors most of the biodiversity. In recent years, marine natural products have yielded a considerable number of drug candidates. Marine microorganisms, whose genetic and biochemical diversity became a rich source of novel chemical entities for the discovery of more effective drugs. Marine microbes especially marine sponges are playing a unique contribut...
A solid dispersion is the dispersion of one or more active ingredients in an inert carrier or matrix at solid state prepared by melting, solvent, or melting-solvent Method. The poor solubility of drug substances in water and their low dissolution rate in the aqueous gastro-intestinal fluids often lead to insufficient bioavailability. If the dissolution rate of the active ingredient in the gastroin...
Mouth dissolving tablet disintegrates within a minute without drinking water. The purpose of present work was to develop a patient-friendly tablet for antihypertensive treatment using Benazepril HCl was taste masked by complexing with indion 204 and formulate as mouth dissolving tablet (MDT). The formulated drug-resin complex was characterized by IR, DSC, etc. Overall nine mouth dissolving formula...