Volume 4 (2018) - Issue 11, November
Over the last decade, the public has become increasingly aware of the potentially dangerous, systemic side effects of pain medication. Even readily available over-the-counter drugs like acetaminophen, ibuprofen, and aspirin can cause serious damage to the digestive system as a result of long term usage and/or high dosage. A possible alternative to pills for pain relief is transdermal drug delive...
Dietary polyphenols, mainly phenolic acids and flavonoids, are the primary sources of antioxidants that can be generally recommended for human consumption. Polyphenols are derived from plant-based food, including fruits, vegetables, spices, herbs, etc. In the present era, there has been a great interest in the health benefits of dietary polyphenols against oxidative stress-related diseases such as...
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, less side effect, easy use, and improved patient compliance. Glimepiride is an anti-diabetic drug with a shorter half-life of ~5 h, low bioavailability, and extensive first-pass metabolism due to these limitations required to maintain the therapeuti...