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A STUDY TO ASSES THE ANTIBACTERIAL PROPERTY OF FIVE ENDODONTIC SEALERS
Aim: The study aims to analyze the antibacterial property of various endodontic sealers against Streptococcus mutans and Enterococcus faecilis. Objective: Pulpal tissues are frequently infected by bacteria and are considered to be the commonest etiological agents of pulpal necrosis and periapical lesions, which needs endodontic treatment for its cure. Microorganisms play an important role in endod...
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STABILITY INDICATING SIMULTANEOUS ESTIMATION OF METFORMIN AND EMPAGLIFLOZIN IN PHARMACEUTICAL TABLET DOSAGE FORM BY RP-HPLC
A simple, rapid, accurate, precise, specific, sensitive and stability indicating RP-HPLC method has been developed and validated for the simultaneous estimation of Metformin and Empagliflozin in bulk drug and pharmaceutical dosage form. The chromatographic separation was performed on the Kromasil C18 column (250mm×4.6mm, 5μm particle size), using a mobile phase of buffer: Acetonitrile taken in t...
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IN VITRO ANTI HAEMOLYTIC, ANTI BACTERIAL AND PHYTO CONSTITUENTS INVESTIGATION OF ANDROGRAPHIS PANICULATA METHANOLIC LEAF EXTRACT
The bitter plant Andrographis paniculata has been selected to evaluate the anti haemolytic activity, antibacterial activity, and various phytochemicals present in the methanolic leaf extract. The leaf extract of Andrographis paniculata shown to have significant anti-haemolytic activity. The extract showed anti-haemolytic activity in the range from 42% to 80%. At varying concentration of plant extr...
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A STUDY ON ASSESSMENT OF PRESCRIBING PRACTICES IN EMERGENCY DEPARTMENT OF A TERITARY CARE TEACHING HOSPITAL
Background: In the emergency department, doctors face urgent and severe cases that need to be treated quickly with high quality. Therefore, clinicians often face challenges in selecting, initiating and individualizing appropriate drug therapy for patients admitted in the emergency medicine ward. Objective: To assess the prescribing patterns of drugs and to determine the rationality of prescription...
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PRESCRIPTION SURVEY: CHOICE OF BENZODIAZEPINES BY THE PSYCHIATRISTS & NEUROLOGISTS IN COMILLA & FENI DISTRICT OF BANGLADESH (MAY 2015)
This prescription survey was carried out to find the most frequently used benzodiazepine class (e.g., Clonazepam, Diazepam, Bromazepam, Clobazam, Midazolam, Flurazepam & Alprazolam) & their rational use as anti-anxiety agents in the Comilla & Feni District of Bangladesh. All the prescriptions were collected in June 2015, prescribed by psychiatrists throughout May 2015. We have found pr...
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GENE PATHWAYS IN CANCER: BEGINNING, ENDING AND THE ACTORS OF THE STORY
The advancements of cancer research if put in a nutshell can be described as: “Cancer is a genetic disease.” From the past two decades, several actors for cancer are identified, their mutations are characterized, and the pathways they control are described. Intricate relations among JAK-STAT, TGF-B, MAPK, Ras, Wnt, Notch, and Hedgehog signaling pathway have a vital role in apoptosis, survival,...
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FORMULATION AND PREPARATION OF TRANSDERMAL PATCHES OF GLIMIPRIDE PART -2
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, less side effect, easy use, and improved patient compliance. Glimepiride is an anti-diabetic drug with a shorter half-life of ~5 h, low bioavailability, and extensive first-pass metabolism due to these limitations required to maintain the therapeuti...
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ANTI MICROBIAL ACTIVITY OF ROOT CANAL SEALER- ANTIBIOTIC COMBINATION ON ENTEROCOCCUS FEACALIS – IN- VITRO STUDY
Aim and objective: The aim of the in-vitro study is to evaluate the Antimicrobial activity of root canal sealant- antibiotic combination on Enterococcus feacalis. Background: Elimination of microorganisms from the root canal system is the one of the most important objectives of RCT. Enterococcus faecalis (EF) has been the most frequently identified species in canals of root-filled teeth with peria...
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ANTI-INFLAMMATORY, ANTI OXIDANT, AND VASODILATING EFFECT OF EVENING PRIMROSE OIL IN TYPE 2 DIABETIC PATIENTS
Type 2 diabetes mellitus (T2DM) consider the most common diseases in modern societies. Natural products or compounds reported as useful remedies for controlling or preventing T2DM are categorized into 5 major groups namely, anti-inflammation products, AMPK activators, insulin secretion stimulators, alpha-glucosidase/ disaccharidase or amylase inhibitors and products acting with an unknown mechanis...
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PREVALENCE OF HYSTERECTOMY IN SOUTH INDIAN POPULATION
Aim: The aim of this study is to analyse the prevalence of hysterectomy in South Indian population. Objective: To survey about the types, causes and complications of hysterectomy in South Indian women population. Background: Hysterectomy is the surgery to remove the uterus. It may also include the removal of cervix, ovaries, Fallopian tubes and other surrounding structures. The survey comprises of...
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