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LEVEL OF SIALIC ACID IN ORAL CANCER PATIENTS
Aim And Objective: This review aims to find the sialic acid level in oral cancer patients. Background: Oral cavity cancer is currently the most frequent cause of cancer-related death among Indian men. It is preceded by oral precancerous conditions like leukoplakia or oral sub mucous fibrosis. Altered cell surface topography is the soul of the malignant cell. Early detection is the key to treat ora...
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ORAL BIOAVAILABILITY IMPROVEMENT USING SOLID DISPERSION TECHNIQUES: A REVIEW
A solid dispersion is the dispersion of one or more active ingredients in an inert carrier or matrix at solid state prepared by melting, solvent, or melting-solvent Method. The poor solubility of drug substances in water and their low dissolution rate in the aqueous gastro-intestinal fluids often lead to insufficient bioavailability. If the dissolution rate of the active ingredient in the gastroin...
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PHARMACOLOGICAL AND PHYTOCHEMICAL IMPORTANCE OF SIDA CORDIFOLIA: A REVIEW
Sida cordifolia is locally known as Bala is one of those precious medicinal herbs of Malvaceae that are still included in un-utilized herbs in spite of the variety of useful pharmacological properties it possesses. Sida cordifolia have anti-inflammatory, anti-ulcer, anti-diabetic, nephroprotective, cytotoxicity, anti-hypercholesterolemia, hepatoprotective, analgesic, anti-stress and adaptogenic ac...
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SIMULTANEOUS ESTIMATION OF IBUPROFEN AND CARISOPRODOL IN SYNTHETIC MIXTURE BY HPTLC METHOD
A Simple, accurate, and precise high-performance thin layer chromatography method for the simultaneous estimation of ibuprofen and carisoprodol in the marketed formulation was developed. The determination was carried on silica gel 60 GF254 HPTLC plates using a mobile phase n-butanol: glacial acetic acid: Acetone (5:2:3 v/v/v). The absorbance of the spots was measured by densitometry at 254 nm. The...
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BIOLOGICAL AND MEDICINAL SIGNIFICANCE OF TRIGONELLA FOENUM-GRAECUM: A REVIEW
Trigonella foenum-graecum, commonly known as Fenugreek, is an annual herb belonging to family Fabaceae. It is cultivated all through the world as a semiarid crop, and its seeds are rich sources of dietary protein fiber, iron B Vitamins, and several other dietary minerals. It has many potential therapeutic applications in the health sector. It contains different kinds of bioactive compounds such as...
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ASSESSMENT OF DRUG USE BY USING WHO’S PRESCRIBING AND HEALTH FACILITY INDICATORS IN KOMBOLCHA HEALTH CENTERS, NORTHEAST ETHIOPIA
Despite the complexity of the drug use, several indicators have been developed, standardized and evaluated by WHO/world health organization, which provides useful means of measuring certain aspects of country’s drug use. These indicators are grouped into three categories, namely; prescribing indicators, patient care indicators, and facility indicators. Objective: The objective of this study wa...
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2023
ANTI-INFLAMATORY ACTIVITY OF STEM AND LEAF JUICE OF ACACIA ARABICA WILD
Herbal drugs constitute a major part in all the traditional systems of medicine. From the literature review, it comes to know that Acacia arabica stem is used as a chewing stick and claimed to be useful for bleeding gums and pain related to it. In some communities use of leaves is also known. The components are taken from live parts as they are, without allowing them to dry for a long period, whic...
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LURASIDONE: A REVIEW OF ANALYTICAL METHODS FOR ESTIMATION IN PHARMACEUTICAL FORMULATION
Lurasidone is an atypical antipsychotic approved by the FDA for the treatment of schizophrenic disorder and depressive episodes linked through bipolar I disorder in adults when used exclusively or in combination with lithium or valproate. Lurasidone is a benzisothiazole antipsychotic, an antagonist at D2, 5-HT2A and 5-HT7 receptors and a partial agonist at 5-HT1A receptors. As with other antipsych...
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FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLET WITH TASTE MASKING RESIN
Mouth dissolving tablet disintegrates within a minute without drinking water. The purpose of present work was to develop a patient-friendly tablet for antihypertensive treatment using Benazepril HCl was taste masked by complexing with indion 204 and formulate as mouth dissolving tablet (MDT). The formulated drug-resin complex was characterized by IR, DSC, etc. Overall nine mouth dissolving formula...
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ANTICANCER ACTIVITY OF TERMINALLIA ARJUNA AGAINST HUMAN CANCER LINE CELL
In-vitro cytotoxicity testing has become an integral aspect of drug discovery because it is a convenient, cost-effective, and predictive means of characterizing the toxic potential of new chemical entities. The early and routine implementation of this testing is a testament to its prognostic importance for humans. Anticancer activity of different concentrations (20-100) of plant extracts Terminali...
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