Posted by admin on Jan 13, 2018 in |
Helminthiasis is prevalent globally, but is more common in developing countries with poorer personal and environmental hygiene. In the human body gastrointestinal tract is the abode of many helminths, but some also live in tissue. They harm the host by depriving him of food, causing blood loss, injury to organs, intestinal or lymphatic obstruction. It is estimated that hundreds of millions of people harbor parasitic worms and one-third of the almost three billion people that live below the poverty line in developing regions of sub-Saharan Africa, Asia, and the Americas are infected with one or more helminth. This review gives an overview of symptoms, diagnosis, treatment, prevalence, and herbs used in...
Read More
Posted by admin on Jan 13, 2018 in |
Background: Mothers’ satisfaction with focused antenatal care service is likely to influence effective utilization and compliance with interventions. Thus, this study is aimed to assess satisfaction with focused antenatal care services among pregnant mothers attending at rural public health centers in Tiyo district, Ethiopia. Methods: A facility-based cross-sectional study design that involved an exit interview was conducted at public health centers in Tiyo district. A total of 386 women were enrolled in the study. Both bivariate and Multivariate logistic regression was carried out to identify the associations of each explanatory variable with the outcome variable. Finally, odds ratio with its 95% confidence interval, and p-value of 0.05 was used to identify significant variables. Results: Overall, 77.2% of pregnant mothers were satisfied with focused antenatal care services in the district. However, lack of drugs supply and vaccine (51%), long waiting time to see health providers (51%), lack of drinking water at the facility (63.1%), and poor laboratory services (56.4%) were identified as the dissatisfying factors at each health facilities. Conclusion:...
Read More
Posted by admin on Jan 13, 2018 in |
The relentlessly beating heart has the greatest oxygen consumption of any organ in the body at rest, reflecting its huge metabolic turnover and energetic demands. The vast majority of its energy is produced and cycled in the form of ATP which stems mainly from oxidative phosphorylation occurring at the respiratory chain in the mitochondria. A part of energy production, the respiratory chain is also the main source of reactive oxygen species and plays a pivotal role in the regulation of oxidative stress. Dysfunction of the respiratory chain is therefore found in most common heart conditions. The pathophysiology of mitochondrial respiratory chain dysfunction in hereditary cardiac mitochondrial disease, the aging heart, in LV hypertrophy and heart failure, and ischemia-reperfusion injury is reviewed. We introduce the practicing clinician to the complex physiology of the respiratory chain, highlight its impact on common cardiac disorders, and review translational pharmacological and non-pharmacological treatment...
Read More
Posted by admin on Jan 13, 2018 in |
A simple, rapid, accurate, precise, specific, sensitive and stability indicating RP-HPLC method has been developed and validated for the simultaneous estimation of Metformin and Empagliflozin in bulk drug and pharmaceutical dosage form. The chromatographic separation was performed on the Kromasil C18 column (250mm×4.6mm, 5μm particle size), using a mobile phase of buffer: Acetonitrile taken in the ratio 45:55 v/v, at a flow rate of 1.1 ml/min at an ambient temperature of 30˚C with the detection wavelength at 226nm. The retention times of Metformin and Empagliflozin were 2.182 min and 2.908 min, respectively. The linearity was performed in the concentration range of 125-750 ppm, 3.12-18.75 ppm each of Metformin and Empagliflozin with a correlation coefficient of 0.999 and 0.999 for Metformin and Empagliflozin respectively. The percentage purity of Metformin and Empagliflozin was found to be 100.59% and 100.07% respectively. The proposed method has been validated for specificity, linearity, range, accuracy, precision, and robustness were within the acceptance limit according to ICH Q2 (R1) guidelines, and the developed method can be...
Read More
Posted by admin on Oct 16, 2017 in |
Background: The population of senior citizens is progressively increasing worldwide due to various factors. As age increases, it causes numerous changes in the functional ability and mobility among senior citizens. Objectives: Assess the level of functional ability and mobility among the senior citizens, correlate the functional ability and mobility among the senior citizens, associate demographic variables with functional ability and mobility. Materials and Methods: The non-experimental research approach of the descriptive design was adopted. The study was conducted at a selected rural community in Bangalore with a sample size of 100. The study participants were selected using a purposive sampling technique of those who fulfill the inclusion criteria. Katz Index of Independence in Activities of Daily Living (ADL), Lawton’s Instrumental Activities of Daily Living (IADL) and TINETTI Performance Oriented Mobility Assessment tool (POMA) (balance and gait) scales were used to collect the data. The collected data were analyzed using descriptive and inferential statistics. Results: Most of the samples (95%) were independent to perform their ADL. 91.3% of females and...
Read More