SYNTHESIS OF SOME NOVEL 2-SUBSTITUTED IMINO-7-SUBSTITUTED PHENYL-3, 7-DIHYDRO-2H-[1, 3] THIAZOLO [5, 4-E] – THIAZIN-5-AMINE AS ANTIFUNGAL ACTIVITYAbstract
The condensation of 2-imino-5 substituted benzylidene-4-thiazolidinone (1) with thiourea (2) in the presence of glacial acetic acid to gives 2-substituted imino-7-substituted phenyl-3,7-dihydro-2H-[1,3] thiazolo [5,4-e]- thiazin-5-amine (3). The antifungal activities of the compounds (3a-h) were tested against A.niger and A. flavus. The growth of both fungi A. niger and A. flavus are inhibited to some extent by all the synthesized compounds. Hence all are antifungal agents.
B. Chaubey *, V. K. Singh, D. Singh, R. K. Varma and V. K. Yadav
Prasad Institute of Technology, Azamgarh Byepass Road Punchhatia, Jaunpur, Uttar Pradesh, India.
21 May 2014
28 July 2014
04 December 2014
01 January 2015