Posted by admin on Jan 15, 2018 in |
Herbal drugs obtained from numerous plants/herbs were extensively utilized in the prevention or treatment of various human ailments since ancient era. Ayurveda, the Indian traditional system of medicine means “science of life and longevity.” The unbeaten heritage of this system is a treasure house of knowledge for both preventive and curative health care available to humankind. It has provided treatment of many diseases using herbs, metals, minerals and formulating them into potent dosage forms. It deals with both prevention and cures the disease of a human being most systematically. Ayurveda is one of the world’s oldest alternative systems of medicines. Herbal products are of interest to many patients and health care practitioners because 70% of the world populations rely on herbal medicines for part of their primary health care system. This research work was designed to evaluate the anti-diabetic activity of Bilwadi Churna (a polyherbal formulation) in streptozotocin-induced diabetic rats and compare with standard drug glibenclamide. In conclusion, it demonstrated that polyherbal formulations have a significant and potent anti-diabetic...
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Posted by admin on Jan 13, 2018 in |
Background: Mothers’ satisfaction with focused antenatal care service is likely to influence effective utilization and compliance with interventions. Thus, this study is aimed to assess satisfaction with focused antenatal care services among pregnant mothers attending at rural public health centers in Tiyo district, Ethiopia. Methods: A facility-based cross-sectional study design that involved an exit interview was conducted at public health centers in Tiyo district. A total of 386 women were enrolled in the study. Both bivariate and Multivariate logistic regression was carried out to identify the associations of each explanatory variable with the outcome variable. Finally, odds ratio with its 95% confidence interval, and p-value of 0.05 was used to identify significant variables. Results: Overall, 77.2% of pregnant mothers were satisfied with focused antenatal care services in the district. However, lack of drugs supply and vaccine (51%), long waiting time to see health providers (51%), lack of drinking water at the facility (63.1%), and poor laboratory services (56.4%) were identified as the dissatisfying factors at each health facilities. Conclusion:...
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Posted by admin on Jan 13, 2018 in |
A simple, rapid, accurate, precise, specific, sensitive and stability indicating RP-HPLC method has been developed and validated for the simultaneous estimation of Metformin and Empagliflozin in bulk drug and pharmaceutical dosage form. The chromatographic separation was performed on the Kromasil C18 column (250mm×4.6mm, 5μm particle size), using a mobile phase of buffer: Acetonitrile taken in the ratio 45:55 v/v, at a flow rate of 1.1 ml/min at an ambient temperature of 30˚C with the detection wavelength at 226nm. The retention times of Metformin and Empagliflozin were 2.182 min and 2.908 min, respectively. The linearity was performed in the concentration range of 125-750 ppm, 3.12-18.75 ppm each of Metformin and Empagliflozin with a correlation coefficient of 0.999 and 0.999 for Metformin and Empagliflozin respectively. The percentage purity of Metformin and Empagliflozin was found to be 100.59% and 100.07% respectively. The proposed method has been validated for specificity, linearity, range, accuracy, precision, and robustness were within the acceptance limit according to ICH Q2 (R1) guidelines, and the developed method can be...
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Posted by admin on Oct 16, 2017 in |
Background: The population of senior citizens is progressively increasing worldwide due to various factors. As age increases, it causes numerous changes in the functional ability and mobility among senior citizens. Objectives: Assess the level of functional ability and mobility among the senior citizens, correlate the functional ability and mobility among the senior citizens, associate demographic variables with functional ability and mobility. Materials and Methods: The non-experimental research approach of the descriptive design was adopted. The study was conducted at a selected rural community in Bangalore with a sample size of 100. The study participants were selected using a purposive sampling technique of those who fulfill the inclusion criteria. Katz Index of Independence in Activities of Daily Living (ADL), Lawton’s Instrumental Activities of Daily Living (IADL) and TINETTI Performance Oriented Mobility Assessment tool (POMA) (balance and gait) scales were used to collect the data. The collected data were analyzed using descriptive and inferential statistics. Results: Most of the samples (95%) were independent to perform their ADL. 91.3% of females and...
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Posted by admin on Oct 16, 2017 in |
The increasing production of cheaper and affordable generic drugs can improve the general healthcare delivery systems as well as decreasing the healthcare costs. Even though there are many generic drug brands available in the market, effective monitoring of the quality of generic drug products marketed are absent in many developing countries. This matter raises a few issues with one of it is the widespread distribution of substandard or counterfeit drug products. Substandard drug products can be defined as genuine drugs manufactured by authorized manufacturers but do not meet the quality specifications fixed for them by national standards. Also, drugs that are have three or more generic brand must be assessed and monitored to ensure its interchangeability with the innovator brand. So this study is covering the quality control tests of paracetamol tablet that are available in the local...
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