Posted by admin on Jan 28, 2017 in |
One of the important aspects of modern toxicology research is the prediction of toxicity of environmental pollutants from their molecular structure A Quantitative Structure Toxicity Relationship (QSTR) study was applied to a dataset of 35 polychlorinated dibenzofurans (PCDFs) to investigate the relationship between toxicities of the compounds and their structures. The molecular descriptors were obtained by Density Functional Theory (DFT) (B3LYP/6-31G*) level of calculation. The QSTR model was built using Genetic Function Algorithm (GFA) method. The model with the best statistical significance (N = 24, Friedman LOF = 0.361, R2 = 0.963, R2adj. = 0.955 R2cv = 0.889, R2pred= 0.8286, P95% ˂ 0.05) was selected. The accuracy of the model was evaluated through Leave one out (LOOV) cross-validation, external validation using test set molecules, Y-randomization, and applicability domain techniques. The prediction results are expected to be useful in predicting and identify structural features responsible for the toxicity of the chemicals and other congeneric compounds that fall within the model’s applicability...
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Posted by admin on Jan 28, 2017 in |
This study has been overviewed to observe the nutritional effect of (Spinacia oleraecea) on human health by consuming it in to various form as raw or cooked because of its antioxidant compound, dietary fiber, minerals vitamins, and iron compound prevents ones health from various diseases anaemia, and also it contains many anticancer agents. It also contains omega 3 fatty acids and anti-inflammatory agent. It is concluded that eating fresh green vegetables prevents many diseases, which results in good...
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Posted by admin on Jan 2, 2016 in |
Aim: The study aims to analyze the antibacterial property of various endodontic sealers against Streptococcus mutans and Enterococcus faecilis. Objective: Pulpal tissues are frequently infected by bacteria and are considered to be the commonest etiological agents of pulpal necrosis and periapical lesions, which needs endodontic treatment for its cure. Microorganisms play an important role in endodontic failures, which is commonly due to incomplete elimination of bacteria from the canal or due to the recolonization of bacteria by leakages. Thus it becomes important for the sealers to have antibacterial property. To make long-lasting restorations, the materials should be made antibacterial. The objective of this study is to check for the antibacterial property of the restorative sealers. Methodology: The antimicrobial activity of five endodontic sealers (zinc oxide eugenol, amalgam, light cure composite, calcium hydroxide, and glass ionomer) was assessed against Enterococcus faecilis and Streptococcus mutans using the agar diffusion method. Reason: Microorganisms being the commonest reason for endodontic treatment failure, endodontic sealers should possess an antimicrobial...
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Posted by admin on Jan 2, 2016 in |
Cardamom is a seed pod, known since antiquity for its culinary and medicinal properties. The spice is native to the evergreen rain forest of southern India and now grown in only a few tropical countries. Cardamom has also been found to regulate inflammatory and immune activities and may be useful for cancer prevention. Cardamom extracts are effective against oral pathogenic bacteria like Streptococcus mutans and Candida albicans. Most people use cardamom as a spice and are largely unaware of its numerous health benefits. This article briefs the various health benefits of...
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