Posted by admin on Mar 13, 2016 in |
The drug discovery and computational advances have helped chemists to develop drugs having utility for specific functional applications along with nutritional aspects. This enables researchers to design formulations and synthesized proper medicines as nutrients. Preparation of nutraceutical formulation that to a veterinary formulation is one of the challenging tasks. Various types of formulations have been devised for sustainable release, easier dissolution with no side effects, and target specific delivery of the chosen drug. The oral administration of veterinary drugs is one of the difficult task, particularly the formulation with the disagreeable smell, taste as well as low nutritional value. Considering these, it was planned to develop easy and likable preparation of nutraceutical formulation of the veterinary drug for easy oral delivery, comprising sustain release of the drug. In the present report, discussion of the formulation of ketoprofen in which veterinary drug is incorporated along with the groundnut or cottonseed oil cake through adsorption method of formulation preparation. Such a formulation can be assimilated effectively by ruminants as the oil...
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Posted by admin on Mar 13, 2016 in |
Background: Medication non-adherence is a growing burden to the health care system in Malaysia. Aim: The study aimed to determine the prevalence, severity, outcome, and factors associated with emergency department (ED) visit due to medication non-adherence at a teaching hospital in Malaysia. Methods: A cross-sectional study design was conducted on patients at the ED of Hospital Universiti Sains Malaysia over six weeks from December 2014 to January 2015. Data were collected using patient interview and review of patient’s medical records. Statistical analysis: Descriptive statistics and multiple logistic regression. Results: Out of the 434 patients on ED visit, 63 (14.5%) [95%CI, 11.0%, 18.0%] were related to medication non-adherence, out of which, 53 (84.1%) experienced severe outcome of the ED visit, 48 (76.2%) were admitted to the ED observation ward, 10 (15.9%) to the hospital ward and 5 (7.9%) were discharged immediately after they have consulted with the ED-physician. Factors associated with the ED visit due to medication non-adherence were: cardiovascular disorder [OR: 7.5 (95%CI 5.3, 11.0)], tuberculosis [OR: 5.5 (95%...
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Posted by admin on Mar 13, 2016 in |
Lurasidone is an atypical antipsychotic approved by the FDA for the treatment of schizophrenic disorder and depressive episodes linked through bipolar I disorder in adults when used exclusively or in combination with lithium or valproate. Lurasidone is a benzisothiazole antipsychotic, an antagonist at D2, 5-HT2A and 5-HT7 receptors and a partial agonist at 5-HT1A receptors. As with other antipsychotics, the exact mechanism of action of lurasidone is unknown, although its effects in schizophrenia are supposed to be related to D2 and 5-HT2A receptor antagonism. This work includes published analytical methods so far reported in the literature, for estimation of lurasidone in biological samples and pharmaceutical formulations. Techniques like UV – Visible Spectrophotometry, high – performance liquid – chromatography (HPLC), high – performance thin – layer chromatography (HPTLC), and Liquid chromatography-mass spectroscopy (LC-MS) with ESI has been used for analysis, from which it can be witnessed that high-performance liquid chromatography methods have been applied most...
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Posted by admin on Feb 13, 2016 in |
Amylase has been exploited in textile, leather, paper, and detergent industries for washing and desizing of fabrics. It was reported to immobilize on to various compatible matrices by adopting various methods to increase its thermal and storage stability. Its immobilization onto bovine serum albumin (BSA) was observed to be very significant to synthesis its non-toxic and low-cost BSA loaded nanoparticles (BSANPs). In this designed washing study, Cicer aritenium amylase loaded butanol driven BSA nanoparticles (BSANPs) were used which were synthesized by using the desolvation method. These synthesized BSANPs were made bio-active with standardized 35U of alkaline protease for their biodegradation to allow the controlled release bound amylase. Then, this bio-active amylase loaded BSANPs were used as nano-wool shampoo additives with chosen woolen shampoo named, Perwoll Shampoo to test the stain removal efficacy from stained woolen fabric without affecting the delicacy and softness of the chosen fabric. In this study, chosen stains were comprised of daily routine stains of boot polish and hair color dye cream named, kiwi leather extra...
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Posted by admin on Feb 13, 2016 in |
Ficus religiosa Linn. is a large evergreen tree found throughout India, wild as well as cultivated, it is widely branched tree with leathery, heart-shaped, long tipped leaves. It is a sacred plant in India. It is one of the most versatile plants having a wide variety of medicinal activities, therefore, used in the treatment of several types of diseases, e.g., diarrhea, diabetes, urinary disorders, burns, hemorrhoids, gastrohelcosis, skin diseases, convulsions, tuberculosis, fever, paralysis, oxidative stress, bacterial infections, etc. This is a unique source of various types of compounds having diverse chemical structure (phenolics, sterols etc.). In this article, we will review the knowledge regarding...
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