Posted by admin on Nov 20, 2015 in |
Aim: To evaluate sleep habits of undergraduate dental students in a private dental college and the relationship between sleep habits and their academic performance. Objective: Sleep patterns and sleep problems amongst dental students have been addressed and related to their academic performance. Materials and methods: A questionnaire on sleep habits, academic performance, and lifestyle were administered. The participants are dental students from Saveetha Dental College. Background: Sleep is a basic drive of nature. Sufficient sleep helps us think more clearly, complete complex tasks better, and more consistently, and enjoy everyday life more fully. Sleep is, in essence, food for the brain, and insufficient sleep can be harmful, even life-threatening. When hungry for sleep, the brain becomes relentless in its quest to satisfy its need and will cause feelings of “sleepiness,” decreased levels of alertness or concentration, and, in many cases, unanticipated sleep. Reason: To analyze the sleeping habits and academic performance of dental college...
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Posted by admin on Aug 19, 2015 in |
Mouth dissolving tablet disintegrates within a minute without drinking water. The purpose of present work was to develop a patient-friendly tablet for antihypertensive treatment using Benazepril HCl was taste masked by complexing with indion 204 and formulate as mouth dissolving tablet (MDT). The formulated drug-resin complex was characterized by IR, DSC, etc. Overall nine mouth dissolving formulations were prepared by direct compression method using three different superdisintegrants viz. croscarmellose sodium, sodium starch glycolate, and crospovidone. The tablets disintegrated in-vitro within 20 s, and the complex drug was released from tablet within 3 min. Formulation F1 to F3 were prepared by direct compression method using sodium starch glycolate as superdisintegrants was found to release the drug in the range of 88.20 to 91.98%. Similarly, formulation F4 to F6, which were prepared by using crospovidone as superdisintegrants showed maximum percent drug release, i.e. 88.27 to 92.68%. Further, F7 to F9 were prepared by using croscarmellose sodium as superdisintegrants and showed percent drug release between 87.72 to 89.18% range. Studies indicated that...
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Posted by admin on Jul 21, 2015 in |
The supply of non-renewable energy sources from fossil fuel is depleting day by day, and it has become one of the greatest challenges to find alternative sources. Bioethanol as alternative biofuels has stimulated the worldwide interest. The use of bioethanol as fuel will minimize the amounts of fossil-derived carbon dioxide (CO2) to the Earth’s atmosphere. Yeast is the most acceptable of all organisms for ethanol production because of its diverse substrate specificity and ease of production of ethanol. Temperature is one of the most important environmental factors affecting microbial activity and production cost. The main objective of this research work was to isolation, characterization, and process optimization of ethanol-producing thermotolerant yeast strains. In total, 5 yeast isolates have been characterized based on morphological and physicochemical characters. Most of the strains were thermotolerant, ethanol tolerant, pH tolerant, as well as osmotolerant. All the strains were formed pseudo mycelium under stress condition. They were resistant to chloramphenicol, but growth was inhibited in the presence of 1% acetic Acid. The strains C...
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Posted by admin on Jul 20, 2015 in |
Objective: To explore the effects of glucose concentration on the growth of Wharton’s jelly mesenchymal stem cells from umbilical cords of gestational diabetic mothers (DWJMSCs) and normal mothers (NWJMSCs). Methods: NWJMSCs and DWJMSCs were treated at passage 3 with low (5.5mM) or high glucose. Cells’ growth was evaluated by methyl thiazolyl tetrazolium uptake and cytotoxicity by LDH release. Status of oxidative stress was estimated by the release of stress enzymes, i.e., glutathione s transferase (GSH) and catalase. Results: The results of cells’ growth assays indicated a significant increase in proliferation in DWJMSCs when treated with high glucose as compared to low glucose while the opposite was found in NWJMSCs. Conversely, cytotoxicity was lower in DWJMSCs treated with 25mM glucose while it was increased in NWJMSCs at the same concentration and vice-versa. Both groups of cells exhibited similar behavior in the release of antioxidant enzymes, i.e., GSH reduced in both cell types at 25mM glucose while no difference was observed in catalase activity. Conclusion: Growth of DWJMSCs is enhanced at...
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Posted by admin on Jul 20, 2015 in |
A prospective observational study was conducted to assess the prescribing pattern of ceftriaxone and to determine the indication for which ceftriaxone prescribed in a general medicine department of a south Indian teaching hospital. A total of 200 prescriptions were collected, collated, and analyzed from the general medicine department for 6 months. Out of 200 study population included in the study, the majority are males. The frequent condition for hospitalization and for which the ceftriaxone was prescribed was respiratory tract infection. The defined daily dosage was proper for 182 patients, and average DDD of ceftriaxone was 2.06. The average total cost incurred for Ceftriaxone per patient was found to be Rs.654.64, for an average of 2.32 days. The prescriber should follow the standard treatment guidelines for improving rational use and to prevent the development of resistance. The specificity of the prescribing pattern of ceftriaxone was more; it means specific therapy was more than empirical therapy. The hospital was largely in compliances with WHO DDDs. The duration of use of ceftriaxone...
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