Posted by admin on Feb 2, 2015 in |
The condensation of 2-imino-5 substituted benzylidene-4-thiazolidinone (1) with thiourea (2) in the presence of glacial acetic acid to gives 2-substituted imino-7-substituted phenyl-3,7-dihydro-2H-[1,3] thiazolo [5,4-e]- thiazin-5-amine (3). The antifungal activities of the compounds (3a-h) were tested against A.niger and A. flavus. The growth of both fungi A. niger and A. flavus are inhibited to some extent by all the synthesized compounds. Hence all are antifungal...
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Posted by admin on Feb 2, 2015 in |
Background: Antiretroviral therapy (ART) is not a cure but it dramatically reduces the rate of morbidity and mortality, and it improves quality of life to people living with HIV/AIDS and it also now considered a manageable chronic disease. Objective: The main objective of this study is to determine the reason for treatment and regimen changes, types of regimen changes, and duration of first initiated antiretroviral regimen among patients on ART. Methods and Materials: The study was conducted retrospectively by reviewing the documentary source of patient and by self-administer questionnaire to health care providers. A sample size of 174 patient records was selected by using systematic sampling. Result: Out of 174 patients’ medical records, the majority were females 112(64.4%). The initial ART regimens used were: Stavudine/ Lamivudine/Nevirapine 78 (44.8%) and Stavudine/Lamivudine/Efavirenz 33(19%). Drug toxicity was the first reason for treatment changes 123(70.7%), followed by Tuberculosis 20(11.5%). The most common toxicities observed were Skin Rash 28(16.1%), Peripheral neuropathy 25(14.4%), Fat change 25(14.4%) and Anemia 18(10.3%). Conclusion: ART regimens are effective in...
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Posted by admin on Feb 2, 2015 in |
The Initial exploratory attempt was made to study the prevalent medicinal flora of Jhansi district of Uttar Pradesh which is a potentially rich heritage of floristic element of medicinal and therapeutical values. The present study deals with angiospermic plants belonging to55 genera and 38 families of Jhansi district for curing various disorders among different ethnic societies. The important genera are Cyperus rotundus (Cyperaceae), Allium cepa (Liliaceae), Argemone Mexicana (Papaveraceae), Azadirachta indica (Meliaceae), Evolvulus alsinoides (Convolvulaceae), Cassia tora (Fabaceae), Achyranthus aspera (Amaranthaceae), Caesalpinia bonduc (Caesalpinaceae), Cleom viscosa (Caparidaceae), Lawsonia inermis (Lythraceae), Ricinus communis (Euphorbiaceae) and Urena lobata (Malvaceae) etc. ,but detailed study was made to evaluate the use and effect of Cyperus rotundus...
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Posted by admin on Feb 2, 2015 in |
Clitoria ternatea, commonly known as Butterfly pea, is a medicinal plant belonging to the family Fabaceae. The plant is reported to be used in lithiasis, insect bites, skin diseases, asthma, burning sensation, ascites, inflammation, leucoderma, leprosy, hemicrania, amentia, and pulmonary tuberculosis. It is commonly called “Shankpushpi” in the Sanskrit language where it is reported to be a good “Medhya” (brain tonic). The major phytoconstituents found in Clitoria ternatea are the pentacyclic triterpenoids such as taraxerol and taraxerone, ternatins, alkaloids, flavonoids, saponins, tannins, carbohydrates, proteins, resins, and starch. Various secondary metabolites including triterpenoids, flavonols, anthocyanins, and steroids have been isolated from Clitoria ternatea...
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