Posted by admin on Jul 20, 2015 in |
Dermatologists should be aware of cosmeceutical products and have access to accurate scientific theory with validated data-if any exists-to support cosmeceutical claims. The question remains whether it is possible to deliver adequate doses to the skin in-vivo and to produce clinical or histological effects. It is important to evaluate these new products with a critical and careful methodology, considering intended product use and the design of available studies supporting product use. The system was optimized with a primary aim to prepare this formulation is to reduce down the concentration of ethanol in formulation by addition of PEG-600 as a co-solvent. All formulations were observed for appearance of color and transparency of gel. The pH of gels was adjusted in the range 6.8 to 7.4. The formulation designed including the ingredients of carbopol 934, PEG (600), ethanol, and water. Evaluation carried out for the formulation with rheological studies. In-vitro diffusion study through flow through diffusion cell method. Drug content uniformity was determined spectrophotometrically. Spreadability indicates that the gel is easily...
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Posted by admin on Jun 13, 2015 in |
Number of thermal power plants in Singrauli MP (India) has changes air composition, water quality and environmental conditions that consequently affected biodiversity, wildlife and migration of livings in the region. Operational thermal power plants produce enormous quantity of pollutants mostly fly ash as a by product of combustion of coal or any pulverized fuel at higher temperature. Industrial effluents contain several heavy metals distrusted the metabolic process of living organism due to easily dispersion and mobilization in environment. The eatables and applicable potential plants and vegetables altered by these heavy metals and concern derivatives which directly and indirectly posing severe risks to human health which, extremely toxic even in low concentration, and will accumulated in organisms and ecosystems. The National Action Plan on Climate Change must tackle properly the subject of power generation, renewable energy and energy competence sources. Increasing public attentiveness is one of the most important ways to conserve biodiversity. This can be accomplished through educational programs, incentive programs, and volunteer monitoring programs. Various organizations NGO’s and...
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Posted by admin on Jun 13, 2015 in |
A reverse phase isocratic HPLC was developed and validated for the determination of levamisole in pure and tablet dosage forms. Method development was carried out on YMC C18 isocratic column, (250 mm × 4.6 mm i.d., particle size 5 μm, maintained at ambient temperature), Shimadzu LC–sol 2010 Prominence Liquid Chromatography. The mobile phase was a mixture of Acetonitrile: methanol 50:50 v/v and the flow rate was set at 1.3 ml/min and UV detection at 236 nm. Validation parameters were evaluated for the method according to the ICH guidelines. In the linearity study, linearity was observed from 2-10 μg/ml with a correlation coefficient of 0.9999 and regression coefficient of 0.999. The limit of detection and limit of quantitation for the method were 0.0209μg/ml and 0.069μg/ml, respectively. The statistical analysis shows that the method was found to be accurate, reliable, simple, and reproducible. The intra and interassay precisions were satisfactory; the values of relative standard deviations did not exceed 2%. The accuracy of the method was proved; the recovery of levamisole...
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Posted by admin on Jun 13, 2015 in |
The aim of the present research work is to design and evaluate controlled release transdermal patches of selected cardiovascular drug Atenolol. To optimize the prepared formulations by different trial approaches. To design and formulate transdermal patch of Atenolol by mercury substrate method using a few selected polymers viz., HPMC, PVP, EVA, Eudragit RS and RL100 in various proportions and Di-n-butyl Phthalate for the release retardant controlled release transdermal patch. Atenolol was chosen as a model drug for study since it possesses near ideal characteristic that a drug must have in formulating a drug delivery system such as low molecular weight, high lipid solubility, effective in low plasma concentration. It also means multiple administrations with subsequent lack of patient...
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Posted by admin on May 2, 2015 in |
This paper deals with the concept of design and implementation of a low-cost model of an arms control moving chair using ATmega8.This moving chair can move forward, backward, left, and right. This is done with the movement (tilt) of the accelerometer, and the chair stops when there is no movement of the accelerometer. The values of the three-dimensional axis of the accelerometer can be varied and adjusted. The programming has been done through AVR compilers and burned into the ATmega8.The ATmega8 receives the information from the accelerometer and transmits it back via RX and TX pins.ATmega8 has also been interfaced to motor driver IC-L293D, wherefrom the connections go to two motors to drive the wheels of the chair. This model has been successfully implemented at a low cost, and it will benefit physically challenged persons, especially with the poor...
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