Posted by admin on Nov 30, 2019 in |
In the present study, four different groundnut varieties such as RS-1 (Rs-1), TAG-3a (Tg-3a), TAG-51 (Tg-51), and TAG-24 (Tg-24) were grown under different geographical places in India. Physicochemical properties of collected groundnut seeds and their extracted oils were determined for their nutritional assay. It was found that the seeds contained in the range of extracted oil, the specific gravity, viscosities, impurities, refractive index and color of the extracted groundnut seed oil were in the range of 39.98-41.9 (±0.4837) 0.9154-0.9164 (± 0.000), 91.56-91.64 (± 0.0365), 0.03-0.05 (± 0.0085), 1.4633-1.4639 (± 0.000) and 1.24-2.2 (± 0.4313) yellow units respectively. AV (mg KOH/g oil), IV (g I2/100 g oil), SV (mg KOH/ g oil), ester value and unsaponifiable matter content (%) of the extracted oil from groundnut seeds were in the range of 2.33-3.38 (± 0.4837), 91.37-93.65 (± 0.9468), 191.0-193.99 (±1.3588), 187.67-191.67 (± 1.9574) and 0.52-0.63 % (± 0.0466) respectively. This study is empirical and on the basis of finding it revealed that groundnut seed oil could be a valuable source of...
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Posted by admin on Nov 30, 2019 in |
We provide evidence of the structural development and distributional pattern of polysaccharides of the anthers in Melia azedarach L. The anthers of Melia azedarach L. is tetrasporangiate and basic type of wall formation is seen, it consists of six wall layers i.e. single layer of epidermis and endothecium, three middle wall layers and one tapetal layer. The primordium consists of a homogenous mass of meristematic cells which has a uniform distribution of insoluble polysaccharides. Sporogenous cells are moderate with PAS-positive and starch grains are present in all the wall layers. Meiocyte shows a moderate amount of carbohydrate with a prominent nucleus. The secretory cells are present near the connective and tapetum. Secretary cells are having abundant starch grains. Tetrahedral tetrads are present with surrounding thick callose walls with rich PAS-positive walls. The secretary type of tapetum is initially single-layered but some of the cells divide periclinally so that it becomes two-layered at vacuolated microspore stage. Middle wall layers are starting to degenerate at the tetrad stage. The pollen grains...
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Posted by admin on Oct 31, 2018 in |
Over the last decade, the public has become increasingly aware of the potentially dangerous, systemic side effects of pain medication. Even readily available over-the-counter drugs like acetaminophen, ibuprofen, and aspirin can cause serious damage to the digestive system as a result of long term usage and/or high dosage. A possible alternative to pills for pain relief is transdermal drug delivery, the transfer of drugs across the skin. Transdermal delivery has the advantage of keeping the drug in the area where it is applied, allowing for a reduced total dose compared to a pill, but there are challenges with the method. The skin evolved as a highly efficient barrier to keep foreign substances out. After a drug gets through the skin, there is the problem of assuring drug is delivered evenly in an effective dose. Current transdermal drug delivery methods such as aspirin creams use chemical enhancers to allow the drugs to pass through the skin. The amount of aspirin that is absorbed by the body is still limited, however,...
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Posted by admin on Oct 30, 2018 in |
Dietary polyphenols, mainly phenolic acids and flavonoids, are the primary sources of antioxidants that can be generally recommended for human consumption. Polyphenols are derived from plant-based food, including fruits, vegetables, spices, herbs, etc. In the present era, there has been a great interest in the health benefits of dietary polyphenols against oxidative stress-related diseases such as diabetes mellitus, cancer, chronic kidney disease, etc. Here, the content presents an overview of dietary polyphenols in the context of relevance to human...
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Posted by admin on Oct 30, 2018 in |
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, less side effect, easy use, and improved patient compliance. Glimepiride is an anti-diabetic drug with a shorter half-life of ~5 h, low bioavailability, and extensive first-pass metabolism due to these limitations required to maintain the therapeutic level it has chosen as a transdermal drug delivery system. To formulate and evaluate the transdermal drug delivery system of Glimepiride using polymers such as tristearin, soya lecithin, and Eudragit RS100 by solvent casting technique. Formulation of transdermal patches of glimepiride and optimization of SLN transdermal patches. Central composite design (CCD) was applied by using design-expert to optimize the composition of tristearin and soya lecithin for transdermal drug delivery. Prepared drug loaded SLNs were evaluated for particle size analysis, DSC, Drug entrapment efficiency, SEM, and in-vitro release studies. The present study of formulation and preparation of transdermal patches of Glimipride to provide better efficiency of drug another dosage...
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