Posted by admin on Apr 30, 2019 in |
Sida cordifolia is locally known as Bala is one of those precious medicinal herbs of Malvaceae that are still included in un-utilized herbs in spite of the variety of useful pharmacological properties it possesses. Sida cordifolia have anti-inflammatory, anti-ulcer, anti-diabetic, nephroprotective, cytotoxicity, anti-hypercholesterolemia, hepatoprotective, analgesic, anti-stress and adaptogenic activity, cardiovascular, anticancer, antibacterial, antimelanogenesis, anticandidal activity, anti-parkinson’s disease, CNS depressant, fat loss, hypotensive, ultrastructure and antioxidant properties. Here, we have reviewed all the reported pharmacological properties and phytoconstituents of this valuable herb to highlight the effectiveness and potentials of this...
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Posted by admin on Apr 30, 2019 in |
Mikania cordata which belongs to the family Asteraceae is a medicinal plant that has been widely distributed through Southeast Asia and Eastern Africa. It possesses various therapeutic properties which include – anti-inflammatory, anti-ulcer, bronco-dilating, analgesic, antibiotic, anti-diarrheal, hepatoprotective, epidermal or skin protective, coagulative, anticarcinogenic, CNS depressant, anti-stress, cytotoxic, insect and scorpion bites and so on. As per from our study, there is no other review paper available till now regarding the pharmacological properties of this plant. Therefore, our paper is the first one to report a review on Mikania cordata. In this paper, along with the pharmacological properties, the other necessary features regarding the plant can be well acknowledged and can be utilized for further research and study...
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Posted by admin on Apr 30, 2018 in |
Transdermal drug delivery system was introduced to overcome the difficulties of drug delivery through the oral route. Despite their relatively higher costs, transdermal delivery systems have proved advantageous for delivery of selected drugs, such as estrogens, testosterone, clonidine, and nitro-glycerine. Transdermal delivery provides a leading edge over injectable and oral routes by increasing patient compliance and avoiding the first-pass metabolism, respectively. Topical administration of therapeutic agents offers many advantages over conventional oral and invasive methods of drug delivery. Skin is an effective medium from which absorption of the drug takes place and enters into systematic circulation over some time. The present article reviews the selection of drug and polymers suitable to be formulated as a transdermal system, advantages, disadvantages of formulation design, and the methods of preparation and evaluation of...
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Posted by admin on Apr 30, 2018 in |
Amlodipine besylate is a major calcium channel blocker for the treatment of hypertension. Solid dispersion Amlodipine besylate (SD-AB) was prepared by using EC, HPMC, and croscarmellose in different ratios. The development of rapidly disintegrating oral tablets of Amlodipine besylate by direct compression method. The tablets were prepared by using direct compression method and evaluated for weight variations, hardness, friability, wetting time, disintegration time, and dissolution study. Although oral disintegrating tablets are much useful in the cases of the geriatric, pediatric, and traveling patient because of no water required for the administration, therefore, the solid dispersions prepared by a solvent evaporation method using EC, HPMC and croscarmellose carrier can be successfully used for the improvement of dissolution of SD-AB and resulted in a faster onset of action as indicated by in-vivo...
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Posted by admin on Jul 12, 2017 in |
For each infection or confusion condition of the patient, a legitimate solution is of prime significance to keep up the patient healthy. To accomplish this, the solution or medication is regulated Conventionally by at least one of a few very much characterized and prominent courses of medication organization Including oral, parenteral, rectal, alveolar, and Ocular and topical. Among these previously mentioned mainstream courses, ordinary oral course of medication organization lies at the highest point of the progression of the customary routes. Now a day’s a large portion of the pharmaceutical researchers are included in building up a perfect DDS. Researchers have prevailed to build up a framework that can be as close to a perfect framework, and it urges the researchers to create a controlled discharge framework. For this, due to the trouble in new medications, more accentuation has been given in growing new medication conveyance frameworks for existing medications and also new compound substances. In present venture in light of controlled and support discharge tranquilize conveyance framework, to...
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