Posted by admin on Oct 31, 2019 in |
Mandragora officinarum (MO) is thought to be one of the magical herbs since the classical period. The plant belongs to the Solanaceae family and popular in Greeks, the Romans, the Arabs and Hebrews. Earlier, it was believed that the plant has evil power. Different ethnic groups worked closely to establish its profound benefits in the traditional medical field. After thorough research on this plant, it was found that the plant has several medicinal properties and has a powerful intoxicating nature. Even, it is familiar for its narcotic and anesthetic characteristics. Not only that the plant can be used in hallucination, but mania, delirium and can also relieve certain joint pains and acts as a healing agent. It’s diversified phytochemistry consisting of alkaloids, nonalkaloids and some sugars. The current article demonstrates its several pharmacological benefits such as narcosis, anesthetic, aphrodisiac, natural healer and hallucinating quality along with its different phytochemical constituents like atropine, hyoscyamine, cuscohygrine, scopolamine, belladonine, some...
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Posted by admin on Sep 30, 2019 in |
Aim: The aim of the study was to evaluate the dental status of diabetic patients. Objective: To evaluate the oral change viz., periodontal status, the status of alveolar bone, gingival status in type-1 and type-2 diabetic patients. Background: The term diabetes mellitus describes a group of disorders characterized by an elevated level of glucose in the blood and abnormalities of carbohydrate, fat and protein metabolism. Oral disorders like periodontitis, tooth loss, gingivitis, salivary dysfunction, dental caries, oral mucosal diseases, dental caries and oral infections like candidiasis, taste and other neurosensory orders are associated with diabetes mellitus. Reason: Diabetes mellitus is an important health care problem. The oral health care providers can have a significant and positive effect on the oral and general health of patients with diabetes...
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Posted by admin on Sep 30, 2019 in |
According to Acharya Charaka and Sushrut, there is no substance in the universe that cannot be used as a drug on the condition of rational use with definite objectives. Grasses are interesting and important plant drugs with potential to be used in therapeutics. Classical texts of Ayurveda are filled with the description of the therapeutic potential of grasses and fact has been recognized by herbalists/botanists all over the world. The grasses are underestimated medicinal repository. Durva is one of the most effective medicinal grass. In the present paper, an effort has been made to work out the therapeutic potential of one of the most primitive plant drugs with a wide range of uses in human...
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Posted by admin on Aug 31, 2019 in |
The aim of the present study was comprehensively establishing the utility of PAMAM dendrimers in solubility enhancement of Flurbiprofen. It can be concluded that PAMAM dendrimers in the solubility of Flurbiprofen but also helped to localize the drug at the site of action and the drug can provide better therapeutic efficacy with lower dose by reducing its adverse effect. From the solubilization study, it was observed that the increase in solubility was due to the dendrimeric complexation or encapsulation. From this paper, it can also be concluded that formulation containing more amount of dendrimer concentration provides a higher flux than formulation containing a lower amount of dendrimer. This may be due to an increased thermodynamic activity of the drug in dendrimic formulation at a lower concentration of...
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Posted by admin on Aug 31, 2019 in |
Green synthesis of silver nanoparticles from naturally occurring biomaterials provides an alternative, eco-friendly and cost-effective means of obtaining nanoparticles. It is an important thrust area for all scientists and has gained importance because it prevents the environment from pollution. Multi-drug resistance is a growing problem in the treatment of infectious diseases and the widespread use of broad-spectrum antibiotics has produced antibiotic resistance for many human bacterial pathogens. Advancement in nanotechnology has opened a new field in nanomedicine, allowing the synthesis of nanoparticles and evaluation of their synergistic effect with pre-existing antibiotics that can be assembled into a complex structure. Novel studies and technologies are developed to understanding the mechanisms of disease for the design of new drugs, but unfortunately, infectious diseases continue to be a major health problem worldwide. Since ancient times, silver was known for its anti-bacterial effects and for centuries it has been used for prevention and control of disparate infections. Now-a-days vancomycin resistance in gram-positive Cocci is a growing global health problem. In the early 1950s,...
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