Posted by admin on May 19, 2016 in |
The current study was performed to study the antibacterial effects of solvent (ethanol, methanol, chloroform, hexane, acetone, petroleum ether) and aqueous extracts of lima bean, horse gram, and jack bean. The phytochemical studies performed on the extracts revealed the presence of alkaloids, steroids, triterpenoids, flavonoids, tannins, phenols, glycosides, and saponins. The antibacterial activity of these extracts was examined using agar well diffusion method. The extracts were studied for activity against pathogenic bacteria, namely P. syringae, E. coli, B. subtilis, E. faecalis, S. aureus, S. typhi, B. cereus, P. aeruginosa. The activity of the extracts against bacterial proliferation was estimated by measuring the zone of inhibition. The highest antibacterial activity among all the extracts tested and all the seeds involved in this study, the ethanol extract of horse gram has exhibited the maximum antibacterial effect against E. coli (12.0 ± 0.29), E. fecalis (11.0 ± 0.29) and B. substilis (10.0 ± 0.34). The results indicate that all three seeds in the discussion here show high potential for commercialization as antibacterial...
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Posted by admin on Apr 24, 2016 in |
In the present study, we were interested in evaluating the effects of copper on morphological features and non- enzymatic antioxidants in the safflower (cv. A-1). The safflower seeds were grown in Hoagland’s solution supplied with the 0.5 µM (control), 25, 50 and 100 µM CuSO4 for 10th and 20th days. The seedlings were harvested after different days (10th and 20th days). The presence of 50 µM and 100 µM concentration of Cu stimulated impaired root growth after 10th and 20th days, while 25 µM Cu was found to be less in inhibiting the root growth. Also, the shoot growth was found to be adversely affected with increased copper concentration. The malondialdehyde content, nonenzymatic antioxidants (flavonoids and polyphenols), and proline were found to be accumulated in both days harvested leaves of safflower’s seedlings. Thus the conclusion reveals that the increase of copper above threshold point affects the plants in a negative...
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Posted by admin on Apr 24, 2016 in |
Introduction: Chromatographic purification methanolic extract of Epipremnum aureum (Linden and Andre) G. S. Bunting by Gas Chromatography-Mass Spectrometry (GC-MS) was done to analyze the phytochemical constituents for further pharmacological uses. Methods: Ten grams of fresh leaves of plant sample was subjected to solvent extraction with methanol and analyzed by GC-MS on a GCMS-2010 Shimadzu instrument with a Restek-5MS column (5% diphenyl- 95% dimethyl polysiloxane, 30m × 0.25mm ID × 0.25µm df). The compounds were separated using helium as carrier gas at a constant flow 1.21ml/min. Results: It provided peaks of thirty different phytochemical compounds with major components namely 12-Methyl-E,E-2,13-octadecadien-1-ol (4.56%), Lanceol, cis (4.59%), alpha.,2,6,6-tetramethyl- (19.28%), 8-Octadecanone (7.27%), Dibutyl phthalate (16.75%), Phytol (4.28%), vitamin E (8.00%) and gamma-Sitosterol (8.07%). Ten compounds are reported to have antioxidant, anti-inflammatory, diuretic, antiulcer, antimicrobial, antifungal and pesticide activities based on Dr. Duke’s phytochemical and ethnobotanical database. Conclusion: This work will help to identify and isolate these bioactive compounds having pharmaceutical and therapeutic value. In the present study, methanolic extract of the leaves of E....
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Posted by admin on Mar 13, 2016 in |
The drug discovery and computational advances have helped chemists to develop drugs having utility for specific functional applications along with nutritional aspects. This enables researchers to design formulations and synthesized proper medicines as nutrients. Preparation of nutraceutical formulation that to a veterinary formulation is one of the challenging tasks. Various types of formulations have been devised for sustainable release, easier dissolution with no side effects, and target specific delivery of the chosen drug. The oral administration of veterinary drugs is one of the difficult task, particularly the formulation with the disagreeable smell, taste as well as low nutritional value. Considering these, it was planned to develop easy and likable preparation of nutraceutical formulation of the veterinary drug for easy oral delivery, comprising sustain release of the drug. In the present report, discussion of the formulation of ketoprofen in which veterinary drug is incorporated along with the groundnut or cottonseed oil cake through adsorption method of formulation preparation. Such a formulation can be assimilated effectively by ruminants as the oil...
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Posted by admin on Mar 13, 2016 in |
Background: Medication non-adherence is a growing burden to the health care system in Malaysia. Aim: The study aimed to determine the prevalence, severity, outcome, and factors associated with emergency department (ED) visit due to medication non-adherence at a teaching hospital in Malaysia. Methods: A cross-sectional study design was conducted on patients at the ED of Hospital Universiti Sains Malaysia over six weeks from December 2014 to January 2015. Data were collected using patient interview and review of patient’s medical records. Statistical analysis: Descriptive statistics and multiple logistic regression. Results: Out of the 434 patients on ED visit, 63 (14.5%) [95%CI, 11.0%, 18.0%] were related to medication non-adherence, out of which, 53 (84.1%) experienced severe outcome of the ED visit, 48 (76.2%) were admitted to the ED observation ward, 10 (15.9%) to the hospital ward and 5 (7.9%) were discharged immediately after they have consulted with the ED-physician. Factors associated with the ED visit due to medication non-adherence were: cardiovascular disorder [OR: 7.5 (95%CI 5.3, 11.0)], tuberculosis [OR: 5.5 (95%...
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