Posted by admin on Jul 12, 2017 in |
Indole derivatives are prepared by heating a mixture of ketone and phenylhydrazine for 1 hour in a water bath. Poured the heated mixture to a flask and added previously boiled acid to it and again heated and stirred for an additional 10 min. Added the mixture to 25 ml of ice water. As an intercellular signal molecule, indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, and resistance to drugs, biofilm formation, and virulence. Indole derivatives show antimicrobial, antidepressant, anticonvulsant, anti-inflammatory, and analgesic...
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Posted by admin on Apr 24, 2016 in |
In the present study, we were interested in evaluating the effects of copper on morphological features and non- enzymatic antioxidants in the safflower (cv. A-1). The safflower seeds were grown in Hoagland’s solution supplied with the 0.5 µM (control), 25, 50 and 100 µM CuSO4 for 10th and 20th days. The seedlings were harvested after different days (10th and 20th days). The presence of 50 µM and 100 µM concentration of Cu stimulated impaired root growth after 10th and 20th days, while 25 µM Cu was found to be less in inhibiting the root growth. Also, the shoot growth was found to be adversely affected with increased copper concentration. The malondialdehyde content, nonenzymatic antioxidants (flavonoids and polyphenols), and proline were found to be accumulated in both days harvested leaves of safflower’s seedlings. Thus the conclusion reveals that the increase of copper above threshold point affects the plants in a negative...
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Posted by admin on Apr 24, 2016 in |
Introduction: Chromatographic purification methanolic extract of Epipremnum aureum (Linden and Andre) G. S. Bunting by Gas Chromatography-Mass Spectrometry (GC-MS) was done to analyze the phytochemical constituents for further pharmacological uses. Methods: Ten grams of fresh leaves of plant sample was subjected to solvent extraction with methanol and analyzed by GC-MS on a GCMS-2010 Shimadzu instrument with a Restek-5MS column (5% diphenyl- 95% dimethyl polysiloxane, 30m × 0.25mm ID × 0.25µm df). The compounds were separated using helium as carrier gas at a constant flow 1.21ml/min. Results: It provided peaks of thirty different phytochemical compounds with major components namely 12-Methyl-E,E-2,13-octadecadien-1-ol (4.56%), Lanceol, cis (4.59%), alpha.,2,6,6-tetramethyl- (19.28%), 8-Octadecanone (7.27%), Dibutyl phthalate (16.75%), Phytol (4.28%), vitamin E (8.00%) and gamma-Sitosterol (8.07%). Ten compounds are reported to have antioxidant, anti-inflammatory, diuretic, antiulcer, antimicrobial, antifungal and pesticide activities based on Dr. Duke’s phytochemical and ethnobotanical database. Conclusion: This work will help to identify and isolate these bioactive compounds having pharmaceutical and therapeutic value. In the present study, methanolic extract of the leaves of E....
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Posted by admin on Apr 24, 2016 in |
Infection is the major problems in a diabetic patient where the healing process are slow down and increases complications. Antiseptics helps to limit the growth of unwanted bacteria (opportunistic pathogen) superficially but do not work in case of deeper infection as its mode of action slows down after some time. The use of antibiotics also emerges multi-drug resistant pathogens, which are considered more dangerous and difficult to treat. Therefore, a new approach to wound therapy is expected that can escape many of the problems associated with current antibiotic treatments. In this regards, genetically engineered bacteria and their products may enhance the natural wound healing process. Wound healing factors like growth factors as well as fibroblast can be incorporated into bacteria genome which will promote healing mechanism speedily. In this aspect, modified bacteria will also prevent the unnecessary growth of the opportunistic pathogen. Many advantages are anticipated from the use of genetically modified organism and its products in wound treatment. The present review is focussed on the various approach of...
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Posted by admin on Apr 29, 2015 in |
Diabetic nephropathy is the leading cause of chronic kidney disease in patients starting renal replacement therapy. Dialysis is the artificial process of getting rid of waste (diffusion) and unwanted water (ultrafiltration) from the blood. This process is naturally done by our kidneys. Dialysis may be used for people who have become ill and have acute kidney failure (temporary loss of kidney function), or for fairly stable patients who have permanently lost kidney function. In dialysis patients, parameters like glucose, creatinine, total protein concentration, triglycerides, and albumin levels are frequently changed before and after the dialysis. The mean values of glucose have far related to the values taken after the dialysis. The mean values are 144.544, 89.082, and 1.545, 1.465 for glucose and creatinine before and after the...
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