Posted by admin on May 19, 2016 in |
The current study was performed to study the antibacterial effects of solvent (ethanol, methanol, chloroform, hexane, acetone, petroleum ether) and aqueous extracts of lima bean, horse gram, and jack bean. The phytochemical studies performed on the extracts revealed the presence of alkaloids, steroids, triterpenoids, flavonoids, tannins, phenols, glycosides, and saponins. The antibacterial activity of these extracts was examined using agar well diffusion method. The extracts were studied for activity against pathogenic bacteria, namely P. syringae, E. coli, B. subtilis, E. faecalis, S. aureus, S. typhi, B. cereus, P. aeruginosa. The activity of the extracts against bacterial proliferation was estimated by measuring the zone of inhibition. The highest antibacterial activity among all the extracts tested and all the seeds involved in this study, the ethanol extract of horse gram has exhibited the maximum antibacterial effect against E. coli (12.0 ± 0.29), E. fecalis (11.0 ± 0.29) and B. substilis (10.0 ± 0.34). The results indicate that all three seeds in the discussion here show high potential for commercialization as antibacterial...
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Posted by admin on May 19, 2016 in |
Liver is a vital organ play a major role in the metabolism and excretion of xenobiotics from the body. Liver injury or liver dysfunction is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. Modern medicine has provided us many drugs that alleviate liver diseases but compared to it herbal medicine; herbal is preferred because they are cost-effective and considered to be a safe approach for treatment with minimal side effects. Herbal medicines have been used in the treatment of liver diseases for a long time. Several herbal preparations are available in the market. Many herbs have been proven to be efficient as hepatoprotective agents while many more are claimed to be hepatoprotective but be deficient in any such scientific substantiation to support such claims. Clinical research in this century has confirmed the efficacy of several plants in the treatment of liver disease. Hence, this review article contributes to the knowledge of reported indigenous plants, which are prevalent...
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Posted by admin on Apr 24, 2016 in |
In the present study, we were interested in evaluating the effects of copper on morphological features and non- enzymatic antioxidants in the safflower (cv. A-1). The safflower seeds were grown in Hoagland’s solution supplied with the 0.5 µM (control), 25, 50 and 100 µM CuSO4 for 10th and 20th days. The seedlings were harvested after different days (10th and 20th days). The presence of 50 µM and 100 µM concentration of Cu stimulated impaired root growth after 10th and 20th days, while 25 µM Cu was found to be less in inhibiting the root growth. Also, the shoot growth was found to be adversely affected with increased copper concentration. The malondialdehyde content, nonenzymatic antioxidants (flavonoids and polyphenols), and proline were found to be accumulated in both days harvested leaves of safflower’s seedlings. Thus the conclusion reveals that the increase of copper above threshold point affects the plants in a negative...
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Posted by admin on Apr 24, 2016 in |
Introduction: Chromatographic purification methanolic extract of Epipremnum aureum (Linden and Andre) G. S. Bunting by Gas Chromatography-Mass Spectrometry (GC-MS) was done to analyze the phytochemical constituents for further pharmacological uses. Methods: Ten grams of fresh leaves of plant sample was subjected to solvent extraction with methanol and analyzed by GC-MS on a GCMS-2010 Shimadzu instrument with a Restek-5MS column (5% diphenyl- 95% dimethyl polysiloxane, 30m × 0.25mm ID × 0.25µm df). The compounds were separated using helium as carrier gas at a constant flow 1.21ml/min. Results: It provided peaks of thirty different phytochemical compounds with major components namely 12-Methyl-E,E-2,13-octadecadien-1-ol (4.56%), Lanceol, cis (4.59%), alpha.,2,6,6-tetramethyl- (19.28%), 8-Octadecanone (7.27%), Dibutyl phthalate (16.75%), Phytol (4.28%), vitamin E (8.00%) and gamma-Sitosterol (8.07%). Ten compounds are reported to have antioxidant, anti-inflammatory, diuretic, antiulcer, antimicrobial, antifungal and pesticide activities based on Dr. Duke’s phytochemical and ethnobotanical database. Conclusion: This work will help to identify and isolate these bioactive compounds having pharmaceutical and therapeutic value. In the present study, methanolic extract of the leaves of E....
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Posted by admin on Apr 24, 2016 in |
Infection is the major problems in a diabetic patient where the healing process are slow down and increases complications. Antiseptics helps to limit the growth of unwanted bacteria (opportunistic pathogen) superficially but do not work in case of deeper infection as its mode of action slows down after some time. The use of antibiotics also emerges multi-drug resistant pathogens, which are considered more dangerous and difficult to treat. Therefore, a new approach to wound therapy is expected that can escape many of the problems associated with current antibiotic treatments. In this regards, genetically engineered bacteria and their products may enhance the natural wound healing process. Wound healing factors like growth factors as well as fibroblast can be incorporated into bacteria genome which will promote healing mechanism speedily. In this aspect, modified bacteria will also prevent the unnecessary growth of the opportunistic pathogen. Many advantages are anticipated from the use of genetically modified organism and its products in wound treatment. The present review is focussed on the various approach of...
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